Plant-Based Formulations & Skin Treatment Solutions

Naturacur Wound Healing provides plant-based, non-steroidal topical solutions designed to support the skin’s natural recovery process. Backed by more than 50 years of research and clinical experience, the WoundCur® system provides targeted support for acute and chronic wounds, compromised skin, and post-procedure recovery*.

The WoundCur® system includes three Step 1 treatment options: WoundCur® Cataplasm Concentrate, WoundCur® Original Gel, and WoundCur® All Clear Gel—followed by WoundCur® Barrier Cream as Step 2. This two-step protocol helps soothe damaged skin, maintain essential hydration, and create a protective environment for recovery.

WoundCur® products are dermatologist and doctor approved, made in the USA, and suitable for all ages and skin types. They contain no steroids, preservatives, artificial dyes, fragrances, or harsh chemical additives. If you are looking for a reliable, soothing solution for skin repair, explore our non steroidal gel and cream formulations.

Dressing with Phosphorylase Kinase Inhibitors

Wound healing in adult skin, a complex process involving many cell types and processes such as epidermal, fibroblastic and endothelial cell proliferation, cell migration, matrix synthesis and wound contraction, almost invariably results in scar tissue formation and wound induration in adult skin. However, it is worth noting that wound healing in embryonic skin involves repair processes that results in essentially perfect regeneration of the damaged tissue (Martin P. Wound healing – aiming for perfect skin regeneration. Science 1997;276:75-81).

Why Does Wound Healing Almost Always Result in Scarring?

Scarring is associated with inflammation, resulting in the secretion of inflammatory cytokines, and growth factors. It is believed that transforming growth factor-beta (TGFβ), which stimulates the conversion of fibroblasts into myofibroblasts, is predominantly responsible for scarring following injury such as burns and surgical trauma. Wound tension and infections, which increase the secretion of TGFβ, are also associated with increased scarring. It is of interest that embryos, with immature inflammatory cells, are incapable of producing TGFβ.

Injurious processes including burns and surgical trauma trigger wound healing processes by energizing transcription activators, such as nuclear factor kappa B (NF-kB). NF-kB is a family of related dimers, which bind to a common sequence on the DNA, the kB site. In the non-activated state these dimers (p50/p65) are located in the cytoplasm. When activated by injurious stimuli, the activated p50/p65 dimers translocate to the nucleus, where they bind to the DNA, resulting in the transcription of over 200 genes involved in the processes of wound healing.

Woundcur® Gel and Barrier Cream Synergizes as Adjunctive Therapy

The process of activating NF-kB dimers in the cytoplasm involves the removal of an inhibitory protein (IkBα) by phosphorylation of its kinase (IkBα) kinase. This is achieved through phosphorylation of IkBα kinase at its serine/threonine sites by phosphorylase kinase (PhK).

Woundcur® Gels and Barrier Cream contain a proprietary preparation derived from Curcumin extract and other plant-based ingredients that provide a potent inhibitor of NF-kB activation, as a well as protection from re-injury of the wound. The gel dressing, available in two versions (Woundcur® Original Gel for severe or Woundcur® All Clear Gel for maintenance) may be used as a topical agent combined with approved dressings for wound healing for ulcers, burns and surgical wounds. Woundcur® Barrier Cream may be applied to add an extra protective layer over the gel.

Adjunctive Solutions to Assist in Fast Wound Healing

The WoundCur® Two-Step Protocol

Step 1: Apply a WoundCur® Gel Treatment

Choose the appropriate gel formulation based on the condition and stage of recovery:

• WoundCur® Cataplasm Concentrate: Our most concentrated formulation, designed for the first application immediately following a medical or cosmetic procedure and during the initial stages of wound recovery. Use as directed by the treating healthcare provider or patient liaison.

• WoundCur® Original Gel: Our most concentrated daily-use gel for acute or chronic wounds and areas requiring advanced recovery support.

• WoundCur® All Clear Gel: A clear, non-staining option for sensitive skin, visible areas, later stages of recovery, and continued maintenance.

Apply a thin, even layer to clean skin. Gently massage when appropriate and allow the formulation to absorb.

Step 2: Apply WoundCur® Barrier Cream

Once the Step 1 treatment has absorbed, apply a thin layer of WoundCur® Barrier Cream. It creates a breathable, protective layer that helps maintain hydration and shield fragile or compromised skin from external irritants.

Repeat the two-step protocol as directed or as needed. Consult a healthcare professional regarding severe, infected, or non-healing wounds.

Adjunctive Support Through Every Stage of Recovery

Successful wound care requires the appropriate balance of targeted topical support, hydration, and protection. The WoundCur® Two-Step protocol allows the treatment to be adjusted as the skin progresses through recovery.